Potential breakthrough
in treatment for cancer, Alzheimer’s, Parkinson’s
and more

US Patent No. 9,174,917, Potential Retinoid-X-Receptor Agonists: Novel Bexarotene Analogs – M09-155L, describes compounds that are more potent analogs and derivatives of Bexarotene (a drug approved to treat T-cell lymphoma) that may provide alternatives to Bexarotene usage. The analogs have higher selectivity and are promising for treatment of various cancers as well as Alzheimer's disease, Parkinson's disease, schizophrenia and other neurodegenerative diseases. This technology has been licensed by Tocris Bioscience and was developed by the team of Drs. Carl Wagner, Peter Jurutka and Pamela Marshall, all in the School of Mathematical and Natural Sciences.

Regents’ Professor improving life-saving vaccines

US Patent No. 9,439,958, Stabilized Virus Like Particles Have Enhanced Mucosal Immunogenicity – M10-069L. Noroviruses are believed to cause approximately 90 percent of epidemic nonbacterial outbreaks of gastroenteritis worldwide. This patent describes a nasal vaccine that
protects against the two main norovirus strains and induces both mucosal and systemic immune responses and methods to prepare enhanced vaccines against other viruses, such as papillomavirus and hepatitis B and C. The technology was developed by Dr. Charles Arntzen, Regents' Professor in the School of Life Sciences and co-director of the Center for Infectious Diseases and Vaccinology in the Biodesign Institute.

Bright idea: Improving screens on electronic devices

US Patent No. 9,076,974, Tridentate Platinum (II) Complexes – M08-056P, describes new materials that can be used to produce organic light emitting diodes (OLEDs), which are used as back-lighting sources in electronic devices such as cell phones and large-screen TVs, as well
as solid state lighting. The new materials specifically address the problem of blue light emission, offering improved efficiencies and stability when compared to existing materials, thus enabling them to last longer. This technology was developed by Dr. Jian Li, associate professor in the School for Engineering of Matter, Transport and Energy.

Innovation to better fabrication of electronics and displays

US Patent No. 9,155,190, Method of Preparing a Flexible Substrate Assembly and Flexible Substrate Assembly Therefrom – M09-057P, describes methods that allow processing of electronics and displays on flexible (plastic) substrates. Since these substrates can distort at the temperatures required to form electrical and optical components, the new method rigidizes and minimizes distortion of the flexible substrate during device fabrication, allowing higher processing temperatures. This enables higher performance of the circuits and displays formed on them. The technology was developed at ASU’s Flexible Electronics and Display Center.